MDMA

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3,4-Methyl​enedioxy​methamphetamine, commonly known as ecstasy, is a psychoactive drug primarily used as a recreational drug. The desired effects include altered sensations and increased energy, empathy, and pleasure. When taken by mouth, effects begin after 30–45 minutes and last 3–6 hours.

“Molly,” the powder or crystal form of MDMA, the chemical used in Ecstasy, has been a popular drug at music festivals this year, CNN reports. Molly, short for molecule, is considered to be pure MDMA, unlike Ecstasy, which generally is laced with other ingredients, such as caffeine or methamphetamine. 

MDMA is illegal in most countries^[14][17] and, as of 2018, has no approved medical uses.^[6][18] Limited exceptions are sometimes made for research.^[15]Researchers are investigating whether MDMA may assist in treating severe, treatment-resistant posttraumatic stress disorder (PTSD) with phase 3 clinical trials to look at effectiveness and safety expected to begin in 2018.^[19] In 2017 the FDA granted MDMA a breakthrough therapy designation^{[note 2]} for PTSD, meaning if studies show promise, a review for potential medical use could occur more quickly.^[23] 

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MDMA was first made in 1912.^[14] It was used to improve psychotherapy beginning in the 1970s and became popular as a street drug in the 1980s.^[14][15] MDMA is commonly associated with dance parties, raves, and electronic dance music.^[24] It is often sold mixed with other substances such as ephedrine, amphetamine, and methamphetamine.^[14] In 2016, about 21 million people between the ages of 15 and 64 used ecstasy (0.3% of the world population).^[25] This was broadly similar to the percentage of people who use cocaine or amphetamines, but fewer than for cannabis or opioids.^[25] In the United States, as of 2017, about 7% of people have used MDMA at some point in their life and 0.9% have used in the last year.^[26]

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